Flos Chrysanthemi
- Name
- Origin
- Where Does It Grow?
- Nature and Flavor
- Identified Active Components / Major Chemical Constituents
- Drug Actions in TCM
- Traditional Uses in TCM
- Pharmacological Actions
- Toxicology
- Administration and Dosage
- Adverse Effect, Side Effects and Cautions
- References
Name
Latin Name: Flos Chrysanthemi
Common Name: Chrysanthemum
Scientific Name: Chrysanthemum morifolium Ramat.
Chinese Name: 菊花
Pinyin Name: ju hua
Origin
The capitate inflorescence of Chrysanthemum morifolium Ramat., a perennial herbal plant of the Compositae family. There are about 30 different species of chrysanthemum worldwide, 17 of which can be found in China, and TCM uses 4 species for medicinal proposes. Besides the flower, its stem, leaf and root can also be used medicinally.1,4
Where Does It Grow?
Chrysanthemum is widely distributed in China. Nowadays, it is mainly cultivated in provinces like Shenxi, Gansu, Henan, Zhejiang, Anhui and Jiangxi. The flower types, harvesting and processing methods may vary according to the production places. Based on the colors, it is also named as yellow chrysanthemum and white chrysanthemum.3,4,5
Nature and Flavor
Chrysanthemum is mild cold in nature, sweet and bitter in flavor, and mainly manifests its therapeutic actions in the lung and liver meridians.2
Identified Active Components / Major Chemical Constituents
Chrysanthemum contains volatile oils, flavones, sesquiterpenes and triterpenes. The volatile oils mainly include borneol, bornyl acetate, chrysanthemon, and camphor. The flavones include apigenin, acacetin, luteolin-7-glucoside, cosmosiin, quercetin, luteolin, diosmetin, and acacetin-7-O-glucoside. The sesquiterpenes include chrysanthediol A, chrysanthediacetates B-C. The triterpenes include taraxasterol, faradiol, (24S)-25-methoxycycloartane-3β,24-diol, 22α-methoxyfaradiol, faradiol α-epoxide and maniladiol. It also contains adenine, choline, amino acids, vitamins and minerals. The levels of volatile oils in chrysanthemum can be varied significantly due to the types and processing methods; white chrysanthemum has a higher flavone level in general.3,4,5In the Pharmacopoeia of People's Republic of China(2010 Edition) - Part I, the level of chlorogenic acid should not less than 0.2%, the luteolin should not less than 0.08%, while the 3,5-O-dicaffeoyl quinic acid should not less than 0.7%, which are the standard qualities of chrysanthemum.
Drug Actions in TCM
Chrysanthemum disperses wind, enhances vision, clears heat and removes harmful substances of the body. 3Traditional Uses in TCM
Pharmacological Actions
Toxicology
When mice were injected abdominally with chrysanthemum extract, acute LD50 was found to be 1.347±0.131g/kg. In a sub-acute toxicity test, when rabbits were fed with chrysanthemum extracts and decoction 20g/kg daily, no obvious change had seen in EEG and phenol red excretion test in the 7th day, while in 10th day, some rabbits developed reduced appetite and diarrhea, and died. 3
Administration and Dosage
Orally, the usual dose of chrysanthemum is 10~15g, which can be in decoction, pill, powder or tea preparations. Traditionally, yellow chrysanthemum is used for dispersing wind and heat pathogens, and white chrysanthemum is for soothing liver and promoting vision. White chrysanthemum is often used for infusing tea.2,3
Adverse Effect, Side Effects and Cautions
Individuals who are sensitive to low temperatures, or have loose bowels or weak stomach should use chrysanthemum with caution.3,5
References
5. http://www.zysj.com.cn/zhongyaocai/yaocai_j/juhua.html